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ZP - ATP (Adenosine Triphosphate) Microbiosensors for Neuroscience Research

Updated: Mar 5

ZP produces a range of microbiosensors, which have been exploited in Neuroscience Research. In the list of references below are academics papers and publications using the ZP ATP microbiosensor.


# Papers published using ATP biosensors

- Martins Sá, R. W., S. M. Theparambil, K. M. dos Santos, I. N. Christie, N. Marina, B. V. Cardoso, P. S. Hosford and V. R. Antunes (2023). "Salt-loading promotes extracellular ATP release mediated by glial cells in the hypothalamic paraventricular nucleus of rats." Molecular and Cellular Neuroscience 124: 103806.

- Chakrabarty, B., K. Aitchison, P. White, C. J. McCarthy, A. J. Kanai and C. H. Fry (2022). "Frequency-dependent characteristics of nerve-mediated ATP and acetylcholine release from detrusor smooth muscle." Experimental Physiology 107(4): 350-358.

- Price, G. W., J. A. Potter, B. M. Williams, C. L. Cliff, M. J. Wall, C. E. Hills and P. E. Squires (2021). Examining Local Cell-to-Cell Signalling in the Kidney Using ATP Biosensing. Stem Cell Renewal and Cell-Cell Communication: Methods and Protocols. K. Turksen. New York, NY, Springer US: 135-149.

- Potter, J. A., G. W. Price, C. L. Cliff, C. R. Green, P. E. Squires and C. E. Hills (2021). "Collagen I Modifies Connexin-43 Hemichannel Activity via Integrin α2β1 Binding in TGFβ1-Evoked Renal Tubular Epithelial Cells." International Journal of Molecular Sciences 22(7): 3644.

- Squires, P. E., G. W. Price, U. Mouritzen, J. A. Potter, B. M. Williams and C. E. Hills (2021). "Danegaptide Prevents TGFβ1-Induced Damage in Human Proximal Tubule Epithelial Cells of the Kidney." International Journal of Molecular Sciences 22(6): 2809.

- Price, G. W., C. E. Chadjichristos, P. Kavvadas, S. C. W. Tang, W. H. Yiu, C. R. Green, J. A. Potter, E. Siamantouras, P. E. Squires and C. E. Hills (2020). "Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease." Cell Communication and Signaling 18(1): 79.

- Beamer, E. and T. Engel (2020). Using Amperometric, Enzyme-Based Biosensors for Performing Longitudinal Measurements of Extracellular Adenosine 5-Triphosphate in the Mouse. Purinergic Signaling: Methods and Protocols. P. Pelegrín. New York, NY, Springer New York: 197-207.

- McCarthy, C. J., Y. Ikeda, D. Skennerton, B. Chakrabarty, A. J. Kanai, R. I. Jabr and C. H. Fry (2019). "Characterisation of nerve-mediated ATP release from bladder detrusor muscle and its pathological implications." British Journal of Pharmacology 176(24): 4720-4730.

- Tiwari, S., V. Sharma, M. Mujawar, Y. K. Mishra, A. Kaushik and A. Ghosal (2019). "Biosensors for Epilepsy Management: State-of-Art and Future Aspects." Sensors 19(7): 1525.

- McCarthy, C. J., C. Marangos, C. H. Fry and Y. Ikeda (2019). "ATP transients accompany spontaneous contractions in isolated guinea-pig detrusor smooth muscle." Experimental Physiology 104(11): 1717-1725.

- Palygin, O., D. V. Ilatovskaya, V. Levchenko, C. A. Klemens, L. Dissanayake, A. M. Williams, T. S. Pavlov and A. Staruschenko (2018). "Characterization of purinergic receptor expression in ARPKD cystic epithelia." Purinergic Signalling 14(4): 485-497.

- Moehring, F., Cowie, A., Menzel, A., Weyer, A., Grzybowski, M., Arzua, T., Geurts, A., Palygin, O. and Stucky, C. (2018). Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling. eLife, 7.

- Sheikhbahaei S, Turovsky EA, Hosford PS, Hadjihambi A, Theparambil SM, Liu B, Marina N, Teschemacher AG, Kasparov S, Smith JC, Gourine AV (2018) Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity. Nature Communications 9: 340.

- Beamer E, Kovács G, Sperlágh B (2017) ATP released from astrocytes modulates action potential threshold and spontaneous excitatory postsynaptic currents in the neonatal rat prefrontal cortex. Brain Research Bulletin 135:129-142.

- Lazutkaite G, Soldà A, Lossow K, Meyerhof W, Dale N (2017) Amino acid sensing in hypothalamic tanycytes via umami taste receptors. Molecular Metabolism 6:1480-1492.

- Palygin O, Evans LC, Cowley AW, Staruschenko A (2017) Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure. JAHA 6:e006658.

- Tan Z, Liu Y, Xi W, Lou H, Zhu L, Guo Z, Mei L, Duan S (2017) Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons. Nature Communications 8:13772.

- Zappia KJ, Garrison SR, Palygin O, Weyer AD, Barabas ME, Lawlor MW, Staruschenko A, Stucky CL (2016) Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes. PLOS ONE 11(3): e0151602.

- Palygin O, Levchenko V, Evans LC, Blass G, Cowley AW, Jr., Staruschenko A (2015) Use Of Enzymatic Biosensors To Quantify Endogenous ATP or H2O2 in the kidney. J Vis Exp: JoVE.

- Pankratov Y, Lalo U (2015) Role for astroglial alpha1-adrenoreceptors in gliotransmission and control of synaptic plasticity in the neocortex. Front Cell Neurosci 9:230.

- Wells JA, Christie IN, Hosford PS, Huckstepp RT, Angelova PR, Vihko P, Cork SC, Abramov AY, Teschemacher AG, Kasparov S, Lythgoe MF, Gourine AV (2015) A Critical Role for Purinergic Signalling in the Mechanisms Underlying Generation of BOLD fMRI Responses. J Neurosci 35:5284-5292.

- Lopatar J, Dale N, Frenguelli BG (2015) Pannexin-1-mediated ATP release from area CA3 drives mGlu5-dependent neuronal oscillations. Neuropharmacology 93:219-228.

- Lalo U, Palygin O, Rasooli-Nejad S, Andrew J, Haydon PG, Pankratov Y (2014) Exocytosis of ATP From astrocytes modulates phasic and tonic inhibition in the neocortex. PLoS Biol 12: e1001747.

- Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Ryan RP, Cowley AW, Jr., Staruschenko A (2013) Real-time electrochemical detection of ATP and H2O2 release in freshly isolated kidneys. Am J Physiol Renal Physiology 305:F134-141.

- Palygin O, Staruschenko A (2013) Detection of endogenous substances with enzymatic microelectrode biosensors in the kidney. Am J Physiol Regulatory, integrative and Comparative Physiology 305:R89-91.

- Heinrich A, Ando R, Turi G, Rozsa B, Sperlagh B (2012) K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study. Br J Pharm 167:1003-1020.

- Schulz SB, Klaft ZJ, Rosler AR, Heinemann U, Gerevich Z (2012) Purinergic P2X, P2Y and adenosine receptors differentially modulate hippocampal gamma oscillations. Neuropharmacology 62:914-924.

- Dale N (2011) Purinergic signaling in hypothalamic tanycytes: Potential roles in chemosensing. Semin Cell Dev Biol 22:237-244.

- Frayling C, Britton R, Dale N (2011) ATP-mediated glucosensing by hypothalamic tanycytes. J Physiol 589:2275-2286.

- Lopatar J, Dale N, Frenguelli BG (2011) Minor contribution of ATP P2 receptors to electrically-evoked electrographic seizure activity in hippocampal slices: evidence from purine biosensors and P2 receptor agonists and antagon sits. Neuropharmacology 61: 25-34.

- Gourine AV, Kasymov V, Marina N, Tang F, Figueiredo MF, Lane S, Teschemacher AG, Spyer KM, Deisseroth K, Kasparov S (2010) Astrocytes control breathing through pH-dependent release of ATP. Science 329:571-575.

- Kluess HA, Stone AJ, Evanson KW (2010) ATP overflow in skeletal muscle 1A arterioles. J Physiol 588:3089-3100.

- Huckstepp RTR, id Bihi R, Eason R, Spyer KM, Dicke N, Willecke K, Marina N, Gourine AV, Dale N (2010) Connexin hemichannel-mediated CO2-dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity. J Physiol 588:3901-3920.

- Huckstepp RTR, Eason R, Sachdev A, Dale N (2010) CO2-dependent opening of connexin 26 and related β connexins. J Physiol 588:3921-3931.

- Rubini P, Milosevic J, Engelhardt J, Al-Khrasani M, Franke H, Heinrich A, Sperlagh B, Schwarz SC, Schwarz J, Norenberg W, Illes P (2009) Increase of intracellular Ca2+ by adenine and uracil nucleotides in human midbrain-derived neuronal progenitor cells. Cell Calcium 45:485-498.

- Huxtable AG, Zwicker JD, Poon BY, Pagliardini S, Vrouwe SQ, Greer JJ, Funk GD (2009) Tripartite Purinergic Modulation of Central Respiratory Networks during Perinatal Development: The Influence of ATP, Ectonucleotidases, and ATP Metabolites. J Neurosci 29:14713-14725.

- Dale N (2008) Dynamic ATP signalling and neural development. J Physiol 586:2429-2436.

- Gourine AV, Dale N, Korsak A, Tian F, Huckstepp R, Spyer KM (2008) Release of ATP and Glutamate in the nucleus tractus solitari mediate pulmonary stretch receptor (Breur-Hering) reflex pathway. J Physiol 586:3963-3978.

- Schock SC, Munyao N, Yakubchyk Y, Sabourin LA, Hakim AM, Ventureyra ECG, Thompson CS (2007) Cortical spreading depression releases ATP into the extracellular space and purinergic receptor activation contributes to the induction of ischemic tolerance. Brain Res 1168:129-138.

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